Set at the Chelsea General Hospital in Portland, Oregon, the show follows the lives of doctors as they push the limits of their abilities and confront their personal and professional failings. Based on a novel by Sanjay Gupta.

• Alfred Molina
• Ving Rhames
• Jamie Bamber
• Jennifer Finnigan
• Keong Sim
• Sarayu Blue
• Emily Swallow
• Bill Irwin