Series Six of The Apprentice was a British reality television series. The series started on BBC One on 6 October 2010 and ran for twelve weekly hour-long episodes, as in all previous years. Following a web-based application, regional auditions and interviews took place during July 2009 in London, Glasgow, Manchester and Birmingham, about 75 candidates were called back for a second round in London and shooting took place in Autumn 2009. There are sixteen participants and the board consists of Alan Sugar, Nick Hewer and Karren Brady. The programme formerly featured Margaret Mountford, who stood down from the role in June 2009. However, she made a guest appearance in Week 11 as an Interviewer.

• Lord Alan Sugar
• Mark Halliley
• Karren Brady
• Tim Campbell