A year after the death of his friend and partner Sherlock Holmes at the hands of Moriarty, Dr. John Watson resumes his medical career as the head of a clinic dedicated to treating rare disorders. However, he soon finds that his old life is not done with him yet.

• Morris Chestnut
• Eve Harlow
• Peter Mark Kendall
• Inga Schlingmann
• Ritchie Coster
• Rochelle Aytes