A series of interconnected short films are the backdrop for a maniac screenwriter who pitches insane storylines featuring some of Hollywood's biggest and brightest. In some countries, like the United Kingdom and the Netherlands, the structure differs. Instead of a pitch, the films are connected by a group of three teenagers searching for the most banned film in the world, Movie 43, which will ultimately lead to the destruction of civilization.

• Witness Protection Films
• Relativity Media
• Dennis Quaid
• Greg Kinnear
• Hugh Jackman
• Kate Winslet
• Jeremy Allen White
• Liev Schreiber
• Naomi Watts
• Anna Faris