The 2021 Extreme Rules was a professional wrestling pay-per-view and livestreaming event produced by WWE. It was the 13th annual Extreme Rules and took place on September 26, 2021, at the Nationwide Arena in Columbus, Ohio. This was the first Extreme Rules to livestream on Peacock and also the first and only Extreme Rules event to be held in September, replacing Clash of Champions that was previously held during that month.

• World Wrestling Entertainment
• Joe Anoa'i
• Fergal Devitt
• Rebecca Quin
• Bianca Crawford
• Luis Martinez
• Stephen Farrelly
• Jeff Hardy
• Ashley Fliehr