UFC 181: Hendricks vs. Lawler II was a mixed martial arts event held on December 6, 2014 at Mandalay Bay Events Center in Las Vegas, Nevada. The main event was a Welterweight championship rematch between champion Johny Hendricks and number one contender Robbie Lawler. Their first fight at UFC 171 ended in a unanimous decision victory in favor of the reigning champion. The Co-main event featured was a Lightweight Championship bout, which also served as the coaches bout for The Ultimate Fighter Season 20, as current champion Anthony Pettis made his first title defense against Gilbert Melendez.

• Zuffa
• Robbie Lawler
• Johny Hendricks
• Anthony Pettis
• Gilbert Melendez
• Travis Browne
• Brendan Schaub
• Todd Duffee
• Anthony Hamilton